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A2A receptor activation upregulates vascular endothelial growth factor (VEGF), promotes angiogenesis in the dermal microvasculature, stimulates fibroblast migration and proliferation, and suppresses inflammatory cytokine release
Side effects are minimal and may include mild bruising at the IV site or a temporary metallic taste during infusion
Abbreviations CM: Citrulline malate NO: Nitric oxide ATP: Adenosine triphosphate MAS: Malate aspartate shuttle MDH: Malate dehydrogenase NIRS: Near infrared spectroscopy PFK: Phosphofructokinase TCA: Tricarboxylic acid HR: Heart rate GI: Gastrointestinal GVT: German volume training VO 2peak : Peak oxygen consumption EMG: Electromyography References Agudelo LZ, Ferreira DM, Dadvar S, Cervenka I, Ketscher L, Izadi M, Ruas JL (2019) Skeletal muscle PGC-11 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance
Wasiluk, T
Because of this, liver failure may be tough to diagnose at first
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